Intermittent Hypoxia Induced Beneficial Cardiovascular Remodeling in Left Ventricular Function of Type 1 Diabetic Rat
نویسندگان
چکیده
منابع مشابه
Inhalation of hydrogen gas attenuates left ventricular remodeling induced by intermittent hypoxia in mice.
Sleep apnea syndrome increases the risk of cardiovascular morbidity and mortality. We previously reported that intermittent hypoxia increases superoxide production in a manner dependent on nicotinamide adenine dinucleotide phosphate and accelerates adverse left ventricular (LV) remodeling. Recent studies have suggested that hydrogen (H(2)) may have an antioxidant effect by reducing hydroxyl rad...
متن کاملHeart Chymase Plays an Important Role in Left Ventricular Remodeling Induced by Intermittent Hypoxia in Mice
Intermittent hypoxia caused by sleep apnea is associated with cardiovascular disease. Chymase has been reported to play an important role in the development of cardiovascular disease, but it is unclear whether chymase is involved in the pathogenesis of left ventricular remodeling induced by intermittent hypoxia. The aim of this study was to evaluate the effect of a novel chymase inhibitor (NK32...
متن کاملChymase plays an important role in left ventricular remodeling induced by intermittent hypoxia in mice.
Intermittent hypoxia caused by sleep apnea is associated with cardiovascular disease. Chymase has been reported to play an important role in the development of cardiovascular disease, but it is unclear whether chymase is involved in the pathogenesis of left ventricular remodeling induced by intermittent hypoxia. The aim of this study was to evaluate the effect of a novel chymase inhibitor (NK32...
متن کاملLeft ventricular dysfunction and remodeling in streptozotocin-induced diabetic rats.
BACKGROUND It is not fully clarified how diabetes mellitus (DM)-induced cardiac dysfunction is associated with histopathological changes of the heart in a long lasting period of DM. METHODS AND RESULTS Eighteen weeks after a streptozotocin injection was given to Wistar - Kyoto rats (D rats), echocardiography and hemodynamic studies including the dobutamine infusion test were performed. After ...
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Introduction: Exercise training has been suggested as a potential non-pharmacological strategy to prevent cardiovascular injuries. However, the role of exercise is controversial in preventing the progression of injuries caused by diabetic cardiomyopathy or their repairing. Therefore, this study aimed to evaluate the effect of aerobic exercise training on left ventricular apoptotic and antioxida...
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ژورنال
عنوان ژورنال: The Anatolian Journal of Cardiology
سال: 2018
ISSN: 2149-2263
DOI: 10.14744/anatoljcardiol.2018.00236